Seekers of Knowledge predstavujú viac ako ostatní deluxe rožíření živej kartové hry Call of Cthulhu. Jedná sa o prvý z novej rady rozšírenia - doteraz vychádzali jednotlivé Asylum packy každý mesiac, teraz bude vychádzať veľké rozšírenie čo 4 mesiace. Nová rozšírenie obsahujú vždy 165 kariet. Rozšírenie je v angličtine.

Seekers of Knowledge populates the hallowed halls of Miskatonic University with nineteen different characters committed to the merits of higher education, the application of science, and a little dabbling in stranger and darker knowledge.
The host of new Miskatonic characters provides the faction dynamic new life in Call of Cthulhu: The Card Game. Many of the characters work well together, gaining greater efficiency the more of their allies enter play. Other cards provide Miskatonic University players reasons to focus solely upon the heroic Investigators, rather than pairing them up with another faction and compromising their Ideals. Altogether, Seekers of Knowledge looks to sound the bell upon a brand new school year full of optimisti.